What Is Dandy-Walker?

  • May 1, 2025
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So What is Dandy-Walker Syndrome?

According to the medical literature, Dandy-Walker Malformation is a rare congenital brain malformation in children that involves the cerebellum.1

Let’s break down the different types of Dandy-Walker: Dandy-Walker Malformation and Dandy-Walker Variant

Medical label What it means in plain English
Dandy-Walker Malformation (a.k.a Dandy-Walker Syndrome) The back part of the brain (the cerebellum) doesn’t form in the usual way and a fluid-filled pouch opens up, blocking normal cereberal spinal fluid (CSF) flow. It’s the classic and usually the most severe form.2
Dandy-Walker Variant Only part of the cerebellum (the vermis) is smaller or under-developed, but the big fluid pouch is not there. Symptoms can be mild or sometimes absent. The term “variant” is falling out of favor because it vague.
Mega cisterna magna The CSF space behind the cerebellum is enlarged, yet the cerebellum itself looks normal. Often an incidental MRI finding.

When we were learning about Dandy-Walker, the doctor used a dumbbell as a reference to visualize the cerebellum. The vermis is the dumbbell handle and in cases of the variant it’s either thin or missing.

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